Compare and contrast the leading strand and the lagging strand .
What type of bond holds the two strands of DNA together? Why is this bond important for DNA replication?
The complementary strand is: 3’-TAAGCTCG-5’
If one strand of DNA has the sequence 5’-ATTCGAGC-3’, what is the complementary strand? Be sure to label the 5’ and 3’ ends.
| Feature | Leading Strand | Lagging Strand | |---------|----------------|----------------| | Direction of synthesis | Continuous 5’→3’ | Discontinuous 5’→3’ (Okazaki fragments) | | Requires multiple primers | No (one primer needed) | Yes (many primers needed) | | Template strand orientation | 3’→5’ (toward replication fork) | 5’→3’ (away from replication fork) |
Let’s dive into the answers and explanations. Question 1: Draw and label a nucleotide. What are the three components?